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In cells expressing US2 or US11, נערות ליווי בצפון the MHC molecules are transported in a retrograde manner again to the cytoplasm, deglycosylated and degraded by the proteasome following ubiquitination (Wiertz et al., 1996). The viral merchandise bind to the MHC molecules and escort them to the translocation equipment, נערות ליווי בקריות where they are transported again into the cytoplasm. Unlike EBNAs-2, 3 and 4, which are sturdy immunogens, EBNA-1 can not elicit a cytotoxic T lymphocyte (CTL) response.

The persistence of EBNA-1 contributes, most probably, to among the virus-related pathologies.

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